The influnce of volume expanison on renal function after relief of chronic unilateral ureteral obstruction
نویسندگان
چکیده
منابع مشابه
Compensatory renal growth after unilateral ureteral obstruction.
Compensatory renal growth after unilateral ureteral obstruction. The accumulation of bulk renal protein, RNA and DNA was studied in mice during a 35-day period of accelerated renal growth in the kidney contralateral to that obstructed by acute ureteral ligation. Control mice were sham-operated and nonoperated. RNA was determined by the method of Monroe and Fleck, DNA after Ceriotti and protein ...
متن کاملRenal damage progresses despite improvement of renal function after relief of unilateral ureteral obstruction in adult rats.
Progression of renal damage after relief of unilateral ureteral obstruction (UUO) has been demonstrated, especially in neonatal rats. We evaluated renal function and renal damage after relief of 3-day UUO in five groups of adult rats: group 1, no treatment; group 2, 3-day UUO; groups 3-5, 3-day UUO followed by relief; group 3, 7-day relief; group 4, 14-day relief; and group 5, 28-day relief. Gl...
متن کاملSimplified Stereological Evaluation of Renal Morphology after Unilateral Ureteral Obstruction
OBJECTIVE AND METHODS This study established a simple stereological method to obtain quantitative information about two- or three-dimensional structures based on observations from kidney sections in the unilateral ureteral obstruction(UUO) model. RESULTS Tubulointerstitial area(TA) and TA/the area of a rectangular field(RA) were raised gradually, but significantly, in the obstructed kidney fr...
متن کاملRenal hydrogen ion secretion after release of unilateral ureteral obstruction.
The effect of 24 h of unilateral ureteral obstruction on HCO3 reabsroption and urinary acidification was studied in dogs. The postobstructed kidney (EK) had a significantly lower glomerular filtration rate and renal plasma flow than the contralateral kidney (CK). Urinary pH prior to HCO3 loading was significantly higher in the EK as was maximal HCO3 reabsorption. Saline loading depressed HCO3 r...
متن کاملL-Endoglin Overexpression Increases Renal Fibrosis after Unilateral Ureteral Obstruction
Transforming growth factor-β (TGF-β) plays a pivotal role in renal fibrosis. Endoglin, a 180 KDa membrane glycoprotein, is a TGF-β co-receptor overexpressed in several models of chronic kidney disease, but its function in renal fibrosis remains uncertain. Two membrane isoforms generated by alternative splicing have been described, L-Endoglin (long) and S-Endoglin (short) that differ from each o...
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ژورنال
عنوان ژورنال: Kidney International
سال: 1974
ISSN: 0085-2538
DOI: 10.1038/ki.1974.58